Journal of Statistics on Health Decision
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7th Statistics on Health Decision Making: Epidemiology
INVITED SPEAKERS S1.01 Missing data and causal inference Kate Tilling, University of Bristol, UK S1.02 Dealing with Multiple Mediators in Causal Mediation Analysis Beatrijs Moerkerke Ghent, Ghent University, Belgium S2.01 Directed acyclic graphs as a causal inference tool: from principles to applications Andreia Leite, National School of Public Health, NOVA University Lisbon, INSA, Portugal S2.02 Robust Indirect Treatment Comparisons: Addressing Unmeasured Confounding with Quantitative Bias Analysis Kate Ren, University of Sheffield, UK S3.01 Epidemiology in the Data Era Nuno Lunet, Institute of Public Health of the University of Porto (EPIUnit / ITR), Portugal S3.02 Local Epidemiology in Action: Turning Data into Public Health Impact Rui Pedro Leitão, Public Health Unit, Local Health Unit of the Aveiro Region (ULS-RA), Portugal S3.03 Informed policies using national epidemiological information systems André Peralta Santos, Directorate-General for Health (DGS), National School of Public Health, NOVA University Lisbon, Portugal BIOMETRY SESSION OF SPE Bio01 Bayesian spatial joint modelling of hospitalizations due to respiratory cancer in Portugal – a disease mapping approach Felipe Barletta, University of Lisbon, Portugal Bio02 Cutoff-Free Estimation of Seroprevalence: A Mixture Model Approach Nuno Sepúlveda, Warsaw University of Technology, Poland Bio03 A Bayesian joint model for multiple (un)bounded longitudinal markers, competing risks, and recurrent events Pedro Miranda-Afonso, Erasmus University Medical Center, Netherlands Bio03 The problem of Bayesian screening from a medical point of view Sandra Ramos, Polytechnic of Porto, Portugal ORAL COMMUNICATIONS OC01 Dynamic prediction of the causal effect of transplantation on survival to prioritize patients on transplant waiting ists: A case study in hepatocellular carcinoma Pedro Miranda-Afonso , Hau Liu, Michele Molinari, Dimitris Rizopoulos OC02 Understanding the trajectory over time of kidney transplants: A risk factor analysis. Maria J. Polidoro , Ana Pinho, Natércia Durão OC03 So many callers, so little truth: A performance-based decision guide Vera Pinto , Carina Silva, Lisete Sousa OC04 Trends in initial pharmacological treatment for chronic obstructive pulmonary disease in Dutch primary care, 2010-21: a repeated cross-sectional study Guilherme Rodrigues , Joana Antão, Qichen Deng, Brenda N. Baak, Alda Marques, Frits M.E. Franssen, Martĳn A. Spruit OC05 Prescribing patterns of general practitioners for initial asthma treatment between 2010 and 2021 in the Netherlands: a population-based study Joana Antão , Guilherme Rodrigues, Qichen Deng, Brenda N. Baak, Lennart Conemans, Alda Marques, Frits M.E. Franssen, Martĳn A. Spruit OC06 SLE-DAS: A comprehensive and reliable measure of lupus disease activity Carla Henriques , Ana Matos, Diogo Jesus, Luís S. Inês OC07 Assessing forensic sexual diagnosis by key epidemiological principles to redress artificial intelligence limitations in forensic medicine Cristiana Palmela Pereira , Mariana Correia, Victória Ionel, Alexandre Francisco, Diana Augusto, Francisco Salvado, Rui Santos OC08 Forensic epidemiology in the courtroom: bone age assessment Cristiana Palmela Pereira , Maria V. Lameiro, Francisco Salvado, Francisco Coutinho, Diana Augusto, Rui Santos OC09 Comparative analysis of facial measurements in normal vs. trisomy 21 fetuses: A statistical approach Ana V. Silva , Mariana S. Pinto, Cátia Lourenço OC10 Impact of livestock-related air pollution on public health: a nationwide study on COVID-19 in the Netherlands Mariana Simões , Julia Taenzer, Lidwien A. Smit, Roel Vermeulen, Julius Fricke, Jelle Zorn, Miriam Gerlofs-Nijland, Lapo Mughini-Gras, Myrna de Rooij OC11 Co-development of epidemiology and artificial intelligence: forensic age estimation Cristiana Palmela Pereira , Raquel Carvalho, Alexandre Francisco, Francisco Coutinho, Francisco Salvado, Cátia Vaz, Valon Nushi, Ana Rodrigues, Rui Santos OC12 Forensic epidemiology in the courtroom: Performance of dental age estimation Cristiana Palmela Pereira , Maria Vitória Lameiro, Patrícia Antunes, Francisco Coutinho, Francisco Salvado, Valon Nushi, Ana Rodrigues, Rui Santos OC13 Preliminary reliability assessment of the exercise and physical activity competence/attitudes, beliefs, and perceptions on physical activity questionnaire Joana R. Sousa , Vera Afreixo, Joana Carvalho OC14 Development and application of a harmonization method for IgG antibody levels against SARS-CoV-2 spike protein: A cohort study in healthcare professionals Ana Leonor Saraiva , Vera Afreixo, Ausenda Machado, Vânia Gaio OC15 Determinants of health care delivery in OECD countries: A robust panel data analysis. Anabela Rocha , M. Cristina Miranda, Manuela Souto de Miranda OC16 Psychometric validation of the Portuguese short form of the paternal breastfeeding self-efficacy scale (BSES-SF): An exploratory factor analysis Marília Rua , Sandra Rodrigues, Rita Leal, Carlos Mascarenhas, Inês Rua, Marta Silva, Cindy-Lee, Joaquim Alvarelhão OC17 Manipulating OMOP CDM databases: the versatility of R Beatriz Lau , Luís M. Silva, Hugo Alonso OC18 Parkinson’s disease in the Netherlands: incidence and spatial variation in 2017-2022 Mariana Simões , Susan Peters; Anke Huss; Sirwan K. Darweesh; Bas Bloem, Roel Vermeulen OC19 Analyzing the efficacy and safety of endovascular therapy for posterior cerebral artery occlusion stroke: A comparative interpretation of outcomes Beatriz M. Monteiro , Tatiana C. Arede, Tiago Gregório OC20 Psychometric evaluation of a questionnaire about health professionals' perception of clinician and patient-reported outcome and experience measures utility in rehabilitation Gabriel M. Costa , Nuno Cordeiro, Eduardo B. Cruz, Anabela I. Pereira, Joaquim Alvarelhão OC21 Reanalysis of existing data on the impact of food on flucloxacillin pharmacokinetics Joana Martins , Pedro Sa-Couto, Bruno Gago OC22 Reassessment of pharmacokinetic parameters using a non-compartmental analysis Joana Martins , Pedro Sa-Couto, Bruno Gago OC23 Mobility across testing services of the Portuguese Community-based Screening Network participants from 2017 to 2022 Inês Viseu , Paula Meireles, Filipa Gomes, Rosa Freitas, Milton Severo OC24 Ten years of integrated continued care at Naturidade Penela: Adapting to changing health demands Rui P. Almeida , Rúben F. N. Salteiro, Ana C. Rodrigues, Rui S. Gonçalves, João P. Figueiredo OC25 Evolution of the health status of patients admitted in Naturidade Penela S.A., national network of continued integrated care in terms of their level of functionality (Barthel index): Prospective study Rui P. Almeida, Rúben Salteiro , Ana C. Rodrigues, João P. Figueiredo, Rui S. Gonçalves OC26 Applicability of left atrial strain parameters for assessing diastolic function and their predictive value in chronic kidney disease – Literature review and meta-analysis Inês Flores, João P. Figueiredo , Telmo Pereira, Joaquim Castanheira OC27 Musculoskeletal and connective tissue disorders triggered by drug use: Insights from literature and pharmacovigilance data Carolina Valeiro, Florence van Hunsel, Joep Scholl, Cristiano Matos OC28 Oral cancer survival in Portugal: A population-based overview (2015-2020) Catarina A. Rodrigues , Teresa Garcia, Luísa C. Lopes, Pedro Silva, Ofélia Godinho, Luís S. Monteiro, Maria J. Bento, Lúcio L. Santos, Maria Costa OC29 From free text to ICD-10 codes in the emergency department: Protocol for evaluation of an AI-based tool Daniela Duarte , Ana J. Gonçalves, Sara Esteves, Mariana Lobo, Afonso Pedrosa, Alberto Freitas OC30 Parish-level socioeconomic deprivation and breast cancer screening outcomes in a Portuguese local health unit Mariana Fialho , Rui Carvalho, João Rocha, Fernando Tavares, Luciano Santos, Mariana Carrapatoso OC31 Estimating thyroid nodule size using incRidGME: A comparative analysis Jorge Cabral , Vanessa Neto, Pedro Macedo, Vera Afreixo, Maria Teresa Herdeiro, Margarida Fardilha, Alexandra Nunes OC32 Burn injuries in older adults (65-74, 75-84 and >85 years old) compared to young adults (18-64 years old): Age-stratified analysis of risk factors and clinical outcomes Bruna P. Morim , Luís G. Pinheiro, Matilde Q. Tavares OC33 Emergency contraception and contraceptive practices among Portuguese youth: A cross-sectional descriptive study Rita Leal , Diana Vieira, Carolina Baptista, Vera Afreixo OC34 SIADAP as a management tool: Impact on the efficiency in the operating room Daniel S. Ramos , Emília L. Silva, Marcos P. Fonte OC35 IL-6 as a differentiating marker in the detection of neonatal sepsis in combination with CRP and PCT Sara Murça, Francisca Ribeiro , Catarina Oliveira, Inês Vivas OC36 Statistical approach to the efficacy of individual cognitive stimulation in Alzheimer's disease: The added value of meta-regression and subgroup analysis Ricardo São João , Susana Justo-Henriques OC37 Psychosocial Risk and Engagement in Early Childhood Professionals: Insights from a Regional Portuguese Study Ricardo São João , Nélia Mendes OC38 Quality indicators in an intensive care unit: Application of statistical analysis for decision making Beatriz C. Martins , Anabela Oliveira OC39 Psychometric validation of the Portuguese version of the food and nutrition literacy scale (E-LAN) for youth Maria J. Batalha , Sara S. Dias, Ana R. Pedro OC40 Mapping tools for healthcare standards - a scoping review Sara Esteves , Daniela Duarte, Ana J. Gonçalves, Mariana Lobo, Mohammad-Ali Abuzuhri, Ana Ferreira, Andreia Teixeira, Andreia Pinto, Camila Dias, Pedro Vieira-Marques
Impact of the Covid-19 pandemic on dispensing of anticoagulant therapy
Direitos de Autor (c) 2022 Vânia Izabel da Veiga Semedo
Analysis of the Decrease of the Patients’ Pain After Regional Block in Post-anaesthesia Care Unit with a Subarachnoid Anaesthesia or a Balanced General Anaesthesia
Direitos de Autor (c) 2021 Sara Pinheiro, Vera Afreixo
P32 - Identification of gait patterns among patients with parkinsonism based on normalized gait obtained using multiple regression models.
Direitos de Autor (c) 2019 Journal of Statistics on Health Decision
A mental health clinician’s primer on statistical mediation and moderation
Statistical literacy is vital to the effective delivery of evidence-based mental healthcare. In this context, mediation and moderation models of mental processes have become increasingly popular, because of their potential to reveal possible causal mechanisms between variables or specific conditions for a given effect to occur. This brief article aims to introduce practicing mental health clinicians to statistical mediation and moderation models, by outlining their conceptual distinction, summarizing the underlying data analysis procedures, and discussing the implications of such models for clinical decision making in mental health practice.
Direitos de Autor (c) 2024 Carlos Carona
Contribution to the translation and reliability analysis of the Self-Administered Amyotrophic Lateral Sclerosis Functional Rating Scale - Revised, for European Portuguese
Objective: To contribute to the translation of the self-administered ALSFRS-R - European Portuguese version (ALSFRS-R: EP), and to analyse its reliability to enable its use by ALS patients in Portugal. Methods: The study was developed in 3 phases. Phase 1: Translation and cultural adaptation of the self-administered ALFRS-R; Phase 2: Content validation by study participants; Phase 3: Exploratory factor analysis (EFA), analysis of its internal consistency and test-retest reliability. Results: According to a panel of experts (N=6), a CVI of 100% were obtained for all ALSFRS-R: EP items. A sample of 18 people with ALS (13 male) fulfilled the test and evaluated its items regarding its clarity, comprehension, difficulty, and relevance, obtaining values varying from 8.6 and 8.9, 8.7 and 8.9, 8.5 and 8.8, and 8.5 and 8.9, respectively. The EFA revealed three factors representing the following domains: (1) bulbar function; (2) fine and gross motor function; and (3) respiratory function. The instrument total score and its subscales presented good internal consistency (Cronbach'sα: ranging from 0.72 to 0.92 in the test; from 0.70 to 0.95 in the retest) and good to excellent test-retest reliability (Kendall tau: ranging from 0.58 to 0.99). Considering the scale total score for the test, no statistical differences were observed between females and males nor between bulbar ALS and medullar ALS. The correlation between the total score and age showed to be significant and negative (-0.53). Conclusions: The Self-Administered ALSFRS-R: EP version was successfully translated, validated, and presented good to excellent reliability results, with similar EFA structure to other studies. It will allow its use by European Portuguese ALS patients, enabling their health professionals to monitor the disease progression at home.
Direitos de Autor (c) 2023 Maria da Assunção Coelho Matos, Isabel Maria Monteiro Costa, Raquel Carmo Portinha, Beatriz Costa Afonso, Katia Coimbra Barbosa, Carla Sofia Lima Gouveia, Pedro Miguel Ferreira Sa-Couto
Physicians' perceptions of psychosocial factors and coping strategies in their ability to work: a multivariate analysis
Background/Objective: Physicians play a crucial role in healthcare systems but face negative impacts from a challenging work environment, leading to burnout. Burnout has negative effects on physician health and patient care. Understanding psychosocial aspects of work and coping strategies used by physicians is essential. Validated tools, including COPSOQ-II, BriefCOPE, and WAI scales, can provide insight into the psychosocial impact of the medical profession. The study aims to use these scales to explore the relationship between job demands (COPSOQ-II), coping strategies (BriefCOPE), and work ability (WAI) among Portuguese physicians. Methods: Participants were recruited through professional associations and organizations with access to physicians, and data was collected via a self-administered web-based questionnaire. Participants’ sociodemographic characteristics were associated with WAI scores through Chi-Square analysis and One-way ANOVA. Outliers were detected through sensitivity analysis, and exploratory and confirmatory factor analyses were performed for the COPSOQ-II and BriefCOPE scales. Associations between WAI scores and COPSOQ-II and BriefCOPE scales were also analyzed. Results: The study surveyed 55 physicians and found that except for sex, there were no significant differences in the work ability index (WAI) by sociodemographic characteristics. Significant differences were found between WAI and higher scores in job purpose, quality of management, and general health, while higher stress, sleep issues, and depressive symptoms were associated with lower WAI groups. Exploratory (EFA) and confirmatory factorial analyses (CFA) were conducted on the BriefCOPE and COPSOQ-II scales, revealing disconnection with the theoretical model. Under EFA, the BriefCOPE items related to theoretical dimension of "dysfunctional coping" are scattered into other coping dimensions, and the empirical model of the COPSOQ-II scale presented a different configuration from its theoretical model, either in the number of dimensions or in the distribution of items by their dimensions. Under CFA, these differences between the theoretical and empirical models are even clearer, as neither dataset fits to its theoretical counterpart without changes. In BriefCOPE, removing self-blaming is sufficient to correct this, while in COPSOQ, a minimum of 9 dimensions needed to be excluded. Even then this result presents unacceptable CFI(Comparative Fit Index), TLI(Tucker-Lewis Index) and RMSEA(Root Mean Square Error of Approximation) values. Conclusions: This study analyzed physician perceptions of workplace environment and job-related and psychosocial factors using a questionnaire. However, the results did not provide any significant findings, and only suggested some possible associations between certain workplace factors, coping abilities, and work ability. The study had a small sample size and further research with larger sample sizes is needed to confirm these findings.
Direitos de Autor (c) 2023 Ana Messias, Marta Estrela, Pedro Couto, Pedro Sá-Couto, Marco Ramos
Relationship between WAI, BriefCOPE and COPSOQII scales: a multivariate analysis on health care professionals
Background/Objective: Individual health and organizational performance are strongly influenced by how people manage stress, or how they cope. Analysis and understanding of bidirectional association of BriefCOPE and COPSOQII and a unidirectional association of these two with “Índice de Capacidade para o Trabalho (ICT)”, a Portuguese version of Work Ability Index (WAI) in a health care professionals (e.g. Physicians, Nurses…) database (incomplete cases: n=909, complete cases: n=652). Methods: The Brief-COPE is a 28 item self-report questionnaire designed to measure effective and ineffective ways to cope with a stressful life event. The psychosocial factors of work were evaluated using the COPSOQII. This questionnaire comprises 76 items divided into 29 scales. The WAI assesses the work ability, considering their health status, physical and mental demands, and work-related resources. To explore the association between Sociodemographic variables, BrieCOPE and COPSOQII with WAI, the chi-squared test (for categorical variables) and the Kruskal-Wallis test (for quantitative variables) were applied. Exploratory Factorial Analysis (EFA) and Confirmatory Factorial Analysis (CFA) methods todetermine the model structure and fitness were also used. Results: The WAI classification for the health care professionals was: poor/moderate (n=123; 18.9%), good (n=349, 53.5%), excellent (n=180, 27.6%). The sociodemographic variables showed no significant association with WAI categories. For the BriefCOPE scale, significant results were found with WAI categories in 8 of 14 dimensions (e.g active coping, denial, and substance use). For the COPSOQII scale, significant results were found with WAI categories in 28 of 29 dimensions (e.g work pace, burnout, and bullying). By EFA, the best model of BriefCOPE (oblimin rotation) with 4 dimensions was obtained, explaining in total 55% of the data variance. The best resulting model for COPSOQII, composed of 7 dimensions (varimax rotation), explains 63% of the total variance. These best models were used to be compared to the respective CFA. The results for the CFAs were not satisfactory given that the CFI and TLI indices were not good. Conclusions: The main conclusion is that the fitting of the models does not have good results, even considering the models proposed by EFA. This might be explained due to the aggregation of all heath care professionals since different types of healthcare professionals have different work environments and demands.
Direitos de Autor (c) 2023 Alina Humenyuk, Inês Baptista, Rodrigo Antunes, Pedro Sá-Couto, Marco Ramos
Self-perceived functioning in relation to existing symptoms 12 months after SARS-COV-2 infection in workers of an industrial facility in Aveiro Region – an observational study.
Background/Objective: Most individuals recover after acute SARS-CoV-2 infection, but some may suffer persistent symptoms with potential medium and long-term consequences. The present study aims to analyze self-perceived functioning concerning existing symptoms 12 months after SARS-CoV-2 infection in workers of an industrial facility in the Aveiro Region. Methods: Observational study, including workers with a positive SARS-CoV-2 RT-PCR/TRAg test. After 12 months of the infection, the occupational health team collected information on sociodemographic variables, manifested symptoms, and perceived functioning assessed using the WHODAS-2.0–12 items - where '12 points' means the highest functioning. Data analysis included descriptive statistics and univariate and multivariate linear regression. Results: Eighty-five workers were infected with SARS-CoV-2, 77.7% were male, with a mean age of 36y1m±9y8m, 36.8% have a higher education level and 17.7% reported at least one chronic condition. Thirty workers (35.3%) reported persistent symptoms, with fatigue (27.7%) and arthralgia (14.4%) being the most described. Whodas 2.0 mean score was 15,7±5,0, and items most frequently reported as presenting limitations were difficulties in working (43.5%), concentrating (35.3%), and walking one kilometer (35.3%). Self-perceived functioning depended on educational level (β=-2.37, CI95% -4.53 ; -0.21) or the existence of a chronic illness (β=3.53, CI95% 0.81 ; 6.24), and the level of functioning is associated with the persistence of symptoms of fatigue (β=4.02, CI95% 1.75 ; 6.29), headache (β=4.13, CI95% 0.84 ; 7.42), and myalgia (β=3.30, CI95% 0.14 ; 6.45). Conclusions: Persistent symptoms 12 months after symptomatic SARS-CoV-2 infection have an influence on self-perceived functioning. Occupational health services should regularly address the assessment of persistent symptoms of SARS-CoV-2 infection to prevent possible impacts on daily activities and participation.
Direitos de Autor (c) 2023 Ana Rita Pádua, José Joaquim Alvarelhão, Marco Gama, João Conde
Exploratory and Inferential Analysis of Children's Eye Defects Screening in the Region of Aveiro
Background/Objective: Amblyopia is one of the leading causes of monocular vision loss in children in Portugal, affecting 1 to 4% of children. Diagnosis and treatment of amblyopia at an early stage can prevent visual impairment, and thus the Children's Eye Defects Screening (CEDS) was implemented in primary care health centres nationwide with the aim to identify children with eye changes capable of causing amblyopia.The primary objectives of this study were to compare the proportion of screenings conducted in the different municipalities and the possible interference of the typology of functional units in adherence to screening. Methods: An exploratory analysis using R Software was performed on the standardised screening data to identify differences between the 11 primary care health centres in the Region of Aveiro. In addition, an inferential analysis was performed using non-parametric tests such as the Kruskal-Wallis test and the Wilcoxon test, both used to verify whether there are significant differences between the analysed groups. Results: It is possible to observe that the results obtained in 2021 were abnormal because of the COVID-19 pandemic, which lead to an increase in the number of screenings in 2022. The family health units had higher numbers of requests generated, screening attendances, and reports than personalised health care units, especially in 2021 and 2022. Most of the screening results were negative, with approximately 10% of screenings being positive and roughly 1% of scans being inconclusive. There also appears to be a growing trend of positive results in some municipalities, which may result from a higher reach to the target population of this screening. Conclusions: The purpose of our statistical analysis was to identify differences between the primary health centres in Region of Aveiro. Our results show that might be useful to perform further studies in order to address potential inequities regarding CEDS access.
Direitos de Autor (c) 2023 Diana Lucas Almeida, Joana Costa dos Santos, Jorge Manuel Silva Marques
Occupational health, well-being and ability to work in a sample of Portuguese Nurses
Background/Objective: Occupational health is a multidisciplinary activity aiming to keep people mentally and physically well and safe at work. In nurses, it has deserved a particular attention, considering the complexity and demanding nature of the job. The current study aims to investigate the association between psychosocial variables, including coping with work (BriefCOPE) and psychosocial factors of work (COPSOQ-II), and ability to work (WAI) among Portuguese nurses. Methods: An observational cross-sectional study with 111 Portuguese nurses was conducted and the outcome measures include socio-demographical variables, COPSOQ, BriefCOPE and WAI. To study the variables presented in the original database, a sociodemographic characterization was performed, followed by an exploratory factor analysis (EFA) to the COPSOQ and BriefCOPE dimensions. To quantify, test and confirm the results obtained in the previous analyses, a confirmatory factor analysis (CFA) was performed. Results: Key coping dimensions were closely associated with better ability to work among nurses, particularly the use of instrumental support, planning, quantitative demands, and emotional demands. The EFA for BriefCOPE suggested a 5-factor structure, which is a slightly different factor structure for the corresponding 3 theoretical dimensions, and the CFA results show that the model is not fit to the data. Regarding the COPSOQ-II scale, the EFA suggested the same 8-factor structure of the original scale’s theoretical model. For this scale, most of values obtained in CFA are consistent with the cut-off values, so a fit of the model to the data is possible. Conclusions: The current study focus on potential factors playing a role in key well-being and coping with work outcomes on the psychosocial characterization of Portuguese nurses.
Direitos de Autor (c) 2023 Diana Lucas, Hugo Senra, Vitor Rodrigues, Pedro Sá-Couto, Marco Ramos
Are coping and workplace psychosocial factors related to work ability in physicians? A PLS-SEM approach
Background/Objective: Over the last few years, new statistical techniques have been developed in the context of multivariate analysis, which are proving to be very useful in the social or health sciences, even marketing. The aim of this work was to study the interplay between 3 scales: BriefCOPE for evaluating coping strategies; COPSOQII for assessing psychosocial factors; and WAI for assessing work ability. Methods: Considering a subpopulation of physicians (n=35) we applied the Partial Least Squares Structure Equations Modelling (PLS-SEM) technique to study the relation between the 3 scales. Results: Regarding the analysis of BriefCOPE and WAI, the only BriefCOPE domain significantly related to WAI was ‘Strategies focused on emotions’ (β=0.329;p=0.038). In COPSOQII and WAI analysis, the COPSOQII domain ‘Health and wellness’ was significantly associated with WAI (β= 0.599; p<0.001) with a strong effect. In final model regarding the three scales, we could observe that the apparent relationship between WAI and ‘Strategies focused on emotions' (BriefCOPE) is mediated by the COPSOQII domain ‘Health and wellness’ (p = 0.047), which shows that there is small effect between the BriefCOPE and WAI. Conclusions: This study is the first to test relationships between these three scales simultaneously. Using a PLS-SEM approach to analyse the data, the results of the present study highlight the central role of ‘Health and wellness’ in work ability and in the mediation between coping ‘Strategies focused on emotions’ and work ability. These data suggest that employers should implement organizational policies that enhance health and well-being in order to achieve better performance from their employees.
Direitos de Autor (c) 2023 Joana Ricardo Pires, Pedro Sá Couto, Pedro Bem-Haja, Marco Ramos
Coping strategies and psychosocial factors at work of Dietitians/Nutritionists: a multivariate analysis approach
Background/Objective: Dietitians and nutritionists, like many healthcare professionals, frequently experience stress, which can be influenced by coping strategies (BriefCOPE) and the psychosocial work environment (COPSOQ-II) and their impact on work ability and stress levels (WAI). The main objective of this short paper is to examine how BriefCOPE and COPSOQ-II scales can be used to study coping with work-related stress among dietitians and nutritionists (n=301), with a focus on exploring the relationship among these scales and WAI. Methods: BriefCOPE is a self-report measure of coping strategies, and it evaluates various coping strategies, including problem-solving, positive reframing, and avoidance coping. COPSOQ-II is a questionnaire that assesses various psychosocial factors related to the work environment, including job demands, job control, social support, and rewards. WAI is a tool used to assess an individual's work ability, considering their health status, physical and mental demands, and work-related resources. BriefCOPE and COPSOQ-II multivariate outliers were removed based on Mahalanobis distance. The sociodemographic characteristics, the BriefCOPE (n=285) and COPSOQ-II (n=233) scales association with WAI scores were analysed through Chi-Square, Kruskal-Wallis and one-way Analysis of Variance (ANOVA) tests. Exploratory (EFA) and confirmatory (CFA) factor analyses were conducted for both scales. Data was analysed using the R software. Results: BriefCOPE and COPSOQ-II dimensions were obtained, and the WAI scores was reduced to three levels: “Poor/Moderate” (n=69; 22.9%), “Good” (n=158; 52.5%), and “Excellent” (n=74; 24.6%). About BriefCOPE and COPSOQ-II dimensions, association with WAI scores revealed 8 and 22 dimensions, respectively, with statistically different distribution among WAI categories. In exploratory factor analysis, for BriefCOPE scale the best model selected was constituted by 4 factors and explained 57% of variance, and for COPSOQ-II scale the best model was constituted by 7 factors and explained 64% of variance. In confirmatory factor analysis, the best models selected for each scale demonstrated better fit values in comparison with the theoretical models. Conclusions: Most of the BriefCOPE and COPSOQ-II dimensions revealed statistically different distribution among WAI categories for the dietitians and nutritionists group. The excellent work capacity is related to the situation of “I almost always do this” for the dimensions of “Active coping”, and “Positive reinterpretation” for BriefCOPE, and with the situations of “Never/almost never” or “Rarely” for the dimensions of “Role conflicts”, “Work/Family conflict”, “Stress”, “Sleeping troubles”, “Depressive symptoms”, and “Bullying” for COPSOQ-II. This indicates that individuals with excellent work capacity frequently experienced active coping and positive reinterpretation, and never or rarely experienced stress, sleeping issues, burnout, and depressive symptoms. For both scales, EFA presented different factor structures when compared to the theoretical ones. Our data do not fit the theoretical models of BriefCOPE and COPSOQ-II scales, but present good results for the models proposed by EFA.
Índice de capacidade para o trabalho (ICT)
Direitos de Autor (c) 2023 Raquel Simões, João Oliveira, Pedro Sá-Couto, Marco Ramos
The dimension reduction power of ClustOfVar: application of the variable cluster analysis technique in a mixed data health database
Background/Objective: Technological evolution is increasingly making real the elements necessary for the daily practice of personalized medicine, an improved vision of health care whose decisions regarding prognosis, diagnosis and therapeutic strategies depend on the patient's various characteristics. This approach leads to the collection and use of information that is broad in extension and complexity, for which dimensionality reduction techniques are imperative, in order to simplify and understand it. This paper aims to show the value of the ClustOfVar technique, a variable clustering technique capable of dealing with mixed data, resulting in data reduction. Through its hierarchical and non-hierarchical approaches, it replaces sample variables with representative synthetic variables. This dimensional reduction can be extended to individuals by applying Ward's method. Methods: The cleaning process of anthropometric, obstetric, vital signs and pubertal status data from 700 participants of the Generation XXI cohort and/or their mothers led to variables being removed (181 down to 105 variables, 82 quantitative and 23 qualitative). Then, the hierarchical technique of the ClustOfVar package was applied, which started by building a hierarchy of variables. The optimal number of clusters was then determined, considering the aggregation level plot and the bootstrap methodology, and each cluster was characterized. The partition into clusters was then tried with the non-hierarchical process. Once the partition was defined, Ward's method was applied, dividing the participants into clusters. We finished with their description according to the synthetic variables. Results: The partition in 8 clusters of variables suggested by the hierarchical technique was chosen, with the first and third cluster being filled mainly by maternal characteristics (relating mainly to menstruation and physical measurements, respectively). While cluster 2 mixes maternal and individual characteristics, cluster 4 contains only patient variables at birth. Cluster 5 is the most diverse, with anthropometric and related measurements of vital signs and blood macromolecules. Cluster 6 has total mass and fat measurements. Finally, cluster 7 is related to pubertal status variables, and cluster 8 includes cholesterol variables. The clustering of individuals results in the creation of specific profiles for each of the 8 clusters of individuals. Conclusions: The ClustOfVar technique accomplishes a data transformation relevant to the dispersion of personalized medicine. However, it lacks the ability to deal with high proportions of missing data and its bootstrap process is very time-consuming.
Direitos de Autor (c) 2023 Natacha Oliveira, Milton Severo
Analysis of Cervical Node Metastasis in Oral Cavity Squamous Cell Carcinoma Patients
Objetivo: O cancro da cavidade oral é um tipo frequente de cancro da cabeça e do pescoço, associado a elevadas taxas de mortalidade em todo o mundo. Um dos principais fatores de prognóstico da doença é a metástase linfonodal regional que está associada a uma redução da taxa de sobrevivência em 50%. Os locais de tumor mais frequentemente associados à metástase dos gânglios linfáticos regionais varia ao longo da literatura. Com base na nossa população, pretendemos tirar conclusões sobre este tópico e compará-lo com investigações recentes. Métodos: Foi realizado um estudo retrospectivo na Consulta de Medicina Oral e Oncologia do Serviço de Estomatologia do Centro Hospitalar Universitário Lisboa Norte, abrangendo pacientes diagnosticados com Carcinoma de Células Escamosas entre Janeiro de 2015 e Abril de 2021. A amostra inclui 151 casos, a maioria dos quais do sexo masculino (≈59%) e com idade média ao diagnóstico (± desvio padrão) de 65 ± 13 anos. Como critérios de elegibilidade, considerámos doentes que tinham fichas clínicas com informação completa, incluindo variáveis sociodemográficas, local do tumor e estadiamento da doença no momento do diagnóstico. Excluímos locais de tumores com apenas dois casos diagnosticados, considerando o risco de enviesamento. Resultados: Os sítios de tumores orais com maior percentagem de casos com linfonodos clínicos positivos (cN+) no momento do diagnóstico foram a gengiva inferior (72,7%, n=16), fundo da boca (66,7%, n=22), orofaringe (64,7%, n=11), trígono retromolar (58%, n=11) e língua ventral (57%, n=16). Os locais com menos casos de cN+ foram lábio inferior (31%, n=4) e lábio superior (n=0). Uma associação semelhante foi encontrada quando considerados tumores operados (pN+): chão da boca (65%, n=13), trígono retromolar (63,6%, n=7), gengiva inferior (46,2%, n=6) e língua ventral (45%, n=9). Os sítios tumorais com menos casos de pN+ foram palato duro (25%, n=1), gengiva superior (16,7%, n=1) e lábio inferior (0 em cada 7 casos). De acordo com o teste exacto de Fisher, não há associação estatisticamente significativa (p=0,1506) entre o sítio primário do tumor e a doença do nó cervical (cN+ ou, sempre que disponível, pN+). Conclusões: Os nossos dados parecem indicar uma associação entre o local do tumor primário e N+, sendo a metástase cervical mais frequente quando o local do tumor era posterior e caudalmente localizado. O lábio inferior teve menos gânglios linfáticos positivos, provavelmente correlacionados com a inclusão no mesmo grupo de mucosas orais e cancros cutâneos. Apesar destas descobertas, a associação não foi estatisticamente significativa.
Direitos de Autor (c) 2023 Leonor Cruz Silva, José Cunha Coutinho, Ricardo Miguel Vieira de São João, Tiago Dias Domingues, Gonçalo Cunha Coutinho, Cecília Caldas, Paulo Palmela, Miguel Nobre, Francisco Salvado
6th Statistics on Health Decision Making: Artificial Intelligence
P01 - How old are you? Are you a minor? Artificial Intelligence on decision making in Forensic Medicine: Where are we? Valon Nushi, Ana Rodrigues, Arlindo Oliveira, Alexandre Francisco, Rui Santos, Cristiana Palmela Pereira P02 - Comparison of therapy for vesiculobullous diseases pemphigus/ pemphigoid: observational study at Unidade Local de Saúde Santa Maria (ULS Santa Maria). Diana Augusto, Cristiana Palmela Pereira, Leonor Ferreira, Matilde Martins, Ana Rodrigues, Paulo Filipe, Rui Santos P03 - Dental trauma and forensic medicine: is the civil and labor Portuguese national disability table update? Diana Augusto, Cristiana Palmela Pereira, Carolina Flamino, Francisco Salvado, Francisco Coutinho, Rui Santos P04 - Outpatient oral surgery. Which NSAIDs/analgesics to prescribe? A systematic review and meta-analysis. Ana Rodrigues, Cristiana Palmela Pereira, Madalena M. Tropa, Diana Augusto, Francisco A. Coutinho, Francisco Salvado, Rui Santos P05 - Retrospective analysis of a case series of patients with traumatic injuries to the temporomandibular joint in Hospital Santa Maria: a medico-legal framework for impairment assessment Ana Rodrigues, Cristiana Palmela Pereira, Sofia Matos, Francisco Salvado, Francisco Coutinho, Rui Santos P06 - Analysis of the progression of age-related macular degeneration using the novel variable influence analysis model Joana D. Martins, Eugénio M. Rocha, Rita A. Coimbra P07 - Evaluation of the antimicrobial resistance in a clinical laboratory: Python software development Gilberto Rosa, Raquel Diaz, Nadia Kruptsala, Bruno Gago P08 - Perspectives for a conversion model of 2 different OCTA devices in diabetic patients with correlated data Rita Coimbra, Ana R. Santos, Inês Pais, Marta Lopes, Torcato Santos, Chingning T. Yamaguchi, Inês Marques, Elizabeth Pearce P09 - Profile of non-communicable disease risk factors among workers in a higher education institution Maria Piedade Brandão, Pedro Sá-Couto, Gonçalo Gomes, Pedro Beça P10 - Physical activity and anxiety facing musical performance - an observational study on young musicians Inês Loureiro, Helena Santana, Joaquim Alvarelhão P11 - Machine learning algorithms for enhanced thyroid disease classification Filipa Santana, Maria da Conceição Costa P12 - Detecting outliers in the clinical pathways of patients with cataracts Alina Humenyuk, Vera Afreixo, Ana H. Tavares, Diogo Raimundo, Heitor Cardoso, Bernardo Marques P13 - Exploring the topological properties of Gait time series as a complementary tool in levodopa dose decision in Parkinson's disease Jhonathan Barrios, Wolfram Erlhangen, Miguel F. Gago, Estela Bicho, Flora Ferreira P14 - Epidemiological study on central venous catheter infections in a burn unit over three years Ana Leonor Saraiva, Daniel Ramos P15 - The Importance of measurement scales continuous versus ordinal in model-based clustering methods a case study on maternal health risk data Blessing U. Ikechukwu, Adelaide Freitas P16 - Extending survival in octogenarian patients through coronary artery bypass grafting: survival analysis using one-sample log-rank test Inês Sousa, Sílvia Diaz, Rui J. Cerqueira, Ana Filipa Ferreira, Mário J. Amorim, Paulo Pinho, André P. Lourenço, António S. Barros, Francisca Saraiva, Adelino Leite-Moreira P17 - The significance of assessing proportional hazard assumption in Cox regression to evaluate sex differences after coronary artery bypass graft Inês Sousa, Sílvia Diaz, Rui J. Cerqueira, Ana Filipa Ferreira, Mário J. Amorim, Paulo Pinho, André P. Lourenço, António S. Barros, Francisca Saraiva, Adelino Leite-Moreira P18 - Simulating the appointment scheduling in primary care services using Poisson distribution Diana A. Vázquez-Limón, Pedro Damião, Adelaide Freitas, Marco Costa, Nélia da Silva P19 - The effects of regular physical activity on musculoskeletal pain improvement: A cross-sectional study Beatriz Lau, Arianna Dalponte, Vera Afreixo P20 - Longitudinal analysis of red blood cells omics data from COVID-19 vaccination Carolina Silva, Joana Saraiva, Cristina Valentim-Coelho, Fátima Vaz, Mohammed H. Semreen, Nelson C. Soares, Deborah Penque, Marília Antunes P21 - Regression trees for analyzing longitudinal health data streams: A comparative study Elsa P. Soares, Inês Sousa P22 - Precision of minimal clinically important improvement (MCII) estimates: comparison of procedures Inês Baptista, Jan T. Kvaløy, Aksel Paulsen, Vera Afreixo, Ingvild Dalen P23 - A method for improving the generation of viral consensus sequences using adaptive models Maria João. P. Sousa, Diogo Pratas P24 - Environmental exposure index for early life exposure assessment tool (ELEAT) Beatriz Costa, Lisete Sousa, Célia Rasga, Astrid Vicente P25 - The impact of balance as a marker of health status in patients with LVEF ≤40 participating in a home-based cardiac rehabilitation programme Carina Rebelo, José. Mesquita Bastos, Vera Afreixo, Ana Abreu P26 - Stratified Cox regression vs. Cox regression with IPW weights: comparing two approaches for the estimation of the effectiveness of COVID-19 seasonal vaccine in the elderly Portuguese population Diana Lucas, Ausenda Machado, Baltazar Nunes, Vera Afreixo, Patrícia Soares P27 - A Poisson distribution-based simulation approach to consultation scheduling Florbela F. Tavares, Manuel S. Graça, Bruno F. Gago, Pedro D. Rebelo P28 - GeneSEA Explorer: a tool for exploring the depths of gene expression data with Shannon entropy analysis Ana M. Gonçalves, Pedro Macedo, Patrício Costa, Nuno S. Osório P29 - Development of a software for metrics analysis in next generation sequencing Pedro Venâncio, Alexandra Lopes, Gabriela Moura P30 - The effects of Prosyntax on children with DLD and ASD Mafalda Azevedo, Alexandrina Martins, Tatiana Pereira, Pedro Sá Couto, Marisa Lousada P31 - Mental health, emotion regulation and body-investment in adults with different weight-profiles Joana Henriques, Hugo Senra P32 - Pain and functional capacity in rheumatoid arthritis with acupuncture and complementary treatment Diana Seixas, Fátima Farinha, Marcos Pacheco da Fonte, Manuel Laranjeira, Marília Rua P33 - Tomographic Image Reconstruction from Projections using Generative AI Maria. V. Reis, Lara Carramate, Silvia De Francesco, Augusto M. F. da Silva P34 - Predicting hospitalization for non-complicated diverticulitis using machine learning Rodrigo Antunes, Luís Silva, José Maria Moreira, Susana Ourô, Filipa Fonseca P35 - Potential of machine learning as a predictor of PI-RADS™ v2.1 classification Inês A. Azevedo, Lara Carramate, Silvia De Francesco P36 - The control of dyslipidemia in patients enrolled in a functional unit in northern Portugal Mariana C. Correia, Ana D. Fernandes, Mariana V. Martins, Estefânia C. Teixeira, Silvia M. Duarte, Rita F. Ribeiro, Fabíola M. Ferreira, Silvia A. Sousa, Carlota L. Saraiva, Ana C. Barbosa P37 - Psychosocial factors determining mental health status in factory workers Íris M. Milheiro, Lúcia S. Costa, Ana Ferreira, António Loureiro, Sílvia Seco, João P. Figueiredo P38 - Machine learning contribution to detection of subarachnoid hemorrhagic stroke in computed tomography Leonardo G. Sequeira, Silvia De Francesco, Milton R. Santos P39 - Mental health in students of polytechnic higher education Ana S. Cruz, Lúcia S. Costa, Ana Ferreira, António Loureiro, Sílvia Seco, João P. Figueiredo P40 - Spatial distribution and determinants of TB incidence among children under five-years-old in Mozambique Nelson Cuboia; Joana Reis-Pardal, Ivan Manhiça, Cláudia Mutaquiha, Marla Amaro, Isabel Pfumo-Cuboia, Luís Nitrogénio, Pereira Zindonga, Benedita José, Aleny Couto, Luís Azevedo P41 - Modeling trajectories of peripheral muscle strength, functional capacity and disease impact in COPD Jorge Cabral, Guilherme Rodrigues, Joana Antão, Alda Marques P42 - Unraveling the signature of lower airway infection associated with COPD exacerbation in the oral microbiota Inês Henriques, Sara Melo-Dias, Alda Marques, Ana Sousa P43 - Preparing for parenthood during pregnancy – search for health literacy in an E-program at Aveiro municipality Marília Rua, Marta Silva, Rita Leal; Carlos Ferreira, Inês Rua, Sandra Rodrigues, Joaquim Alvarelhão P44 - The contribution of artificial intelligence in wound healing monitoring: a scoping review Carina Marques, Maria B. Fernandes, Mariana Barreiro, Mariana Vilaça, Rafaela Silva, Alexandre Rodrigues P45 - Using AI to support professional interventions in community pharmacies Rúben Duarte Pereira, Joana Pinto, Catarina Nunes, António T. Rodrigues P46 - Flu surveillance in Portugal using over-the-counter sales from community pharmacies Rúben Duarte Pereira, Nuno Rodrigues, Joana Moreno, Zilda Mendes, Rafael Vasconcelos, Gustavo T. Borges, António T. Rodrigues
5th Statistics on Health Decision Making: Personalized Medicine
P01 - Analysis of cervical node metastasis in oral cavity squamous cell carcinoma patients Leonor Cruz Silva, José Cunha Coutinho,Gonçalo Cunha Coutinho, Ricardo Miguel Vieira de São João, Tiago Dias Domingues, Cecília Caldas, Paulo Palmela, Miguel Nobre, Francisco Salvado P02 - Odontometrics analysis as tool of Legal Medicine discipline to decide about perfil postmortem of cadavers: apply in a commingled archaeological human population related to 1755 Lisbon’s earthquake Cristiana Palmela Pereira, Valon Nushi, Tatiana Major, Guilherme Borges, Lara Lopes, Lisa Zheng, Ana Rodrigues, Rui Santos P03 - Forensic dental age assessment: effect size on real age forensic medical report Cristiana Palmela Pereira, Valon Nushi, Diana Augusto, Adriana Santos, Mafalda Marques, Sakher J. AlQhatani, Rui Santos P04 - Effect of statins intake in the risk for progression of age-related macular degeneration – a comparison of two Cox regression models applied to the Coimbra Eye Study Rita Coimbra, Patrícia Barreto, Cláudia Farinha, Rufino Silva P05 - Association between the adrenoreceptor β2 gene and pediatric asthma severity – a study of the PACMAN cohort Maria Leonor Caleiro, Patricia Soares, Marília Antunes P06 - Communication strategies used by health professionals and finalist students from health areas with people with aphasia Daniela Jesus, Ana Rita Pinheiro, Pedro Sá-Couto, Maria A. Matos P07 - Association of the practice of contact sports with the development of amyotrophic lateral sclerosis Ana Rita Henriques, Marta Gromicho, Julian Grosskreutz, Magdalena Kuzma-Kozakiewicz, Susanne Petri, Hilmi Uysal, Susana Pinto, Marília Antunes, Mamede de Carvalho, Ruy M. Ribeiro P08 - Self-perceived functioning in relation to existing symptoms 12 months after SARS-COV-2 infection in workers of an industrial facility in Aveiro Region – an observational study. Ana R. Pádua, Marco Gama, João Conde, Joaquim Alvarelhão P09 - Disclosing gene signatures in gliomas via classification and dimensionality reduction methods João F. Carrilho, Roberta Coletti, Marta B. Lopes P10 - Explanatory variables consistency and association strengths in sepsis diagnosis: a methods comparison Vanusa Rocha, Vera Afreixo, Luís Cabral P11 - Identification of the molecular basis of heart failure through Microarray merging Sandra Magalhães, Sílvia O. Diaz, Adelino Leite-Moreira, António S. Barros P12 - What is the predictive value of ambulatory blood pressure monitoring (ABPM) in terms of future cardiovascular events for patients with resistant hypertension? Simão Carvalho, Carlos Costa, Flávio G. Pereira, Susana Lopes, José Mesquita Bastos P13 - STOP-Bang questionnaire as a screening tool for obstructive sleep apnea syndrome in the bariatric population: a meta-analysis Sara Velha, Emília Lima Silva, Maria da Conceição Costa P14 - Brain protection strategies in the surgical treatment of acute type A aortic dissection and the occurrence of intraoperative brain damage - a systematic literature review and meta-analysis Carolina Lança Pereira, Tiago Adrega P15 - Perceived health status of patients in a hyperbaric medicine unit in the north of Portugal António Pedro Ferreira, Filipe Alvarilhão, Paula Inês Rebelo, Manuel Lopes, Óscar Camacho, Joaquim Alvarelhão P16 - Relevance of testing proportional hazard assumption in Cox Regression - Sex differences in long-term survival after coronary artery bypass grafting Inês Sousa, Sílvia Diaz, Rui J. Cerqueira, Ana Filipa Ferreira, Mário J. Amorim, Paulo Pinho, André P. Lourenço, António S. Barros, Francisca Saraiva, Adelino Leite-Moreira P17 - Exploring the impact of sex differences on atrial fibrillation recurrence after catheter ablation using a data-driven approach Sílvia O. Diaz, Ana Inês Aguiar Neves, Augusto Sá Carvalho, Mariana Ribeiro Silva, Gualter Santos Silva, João Almeida, Paulo Fonseca, Marco Oliveira, Helena Gonçalves, Francisco Sampaio, João Primo, Francisca Saraiva, António S. Barros; Ricardo Fontes-Carvalho P18 - Lipidomic profiling of HFpEF patients for the stratification of cardiovascular risk Sílvia O. Diaz, António S. Barros, Pedro Palma, António Angélico-Gonçalves, Francisco Vasques-Nóvoa, Francisca Saraiva, José A Belo, Otília V Vieira, Adelino F Leite-Moreira P19 - Assessing the prognostic value of metabolites in patients with heart failure: a systematic review and meta-analysis Leonel Sousa Neves, Francisca Saraiva, Adelino Leite-Moreira, António S. Barros, Sílvia O. Diaz P20 - Decoding the genetic architecture behind disease heterogeneity: A genome-wide association study and cluster analysis in COPD Guilherme Rodrigues, Rui Marçalo, Gabriela Moura, Vera Afreixo, Alda Marques P21 - Low versus high-resource pulmonary rehabilitation settings in COPD: a retrospective, propensity score-matched, non-inferiority study Joana Antão, Cátia Paixão, Patrícia Rebelo, Ana Machado, Sara Souto-Miranda, Ana Sofia Grave, Cíntia Dias, Guilherme Rodrigues, Tânia Pinho, M. Aurora Mendes, Ana Oliveira, Alda Marques P22 - Evolution of the risk perception of infection by COVID-19 – Evidence from the COVID-19 Barometer: Social Opinion Inês Paixão, Marília Antunes, Patrícia Soares P23 - Relationship between WAI, BriefCOPE and COPSOQII scales: a multivariate analysis on health care professionals Alina Humenyuk, Inês Baptista, Rodrigo Antunes, Pedro Sá-Couto, Marco Ramos P24 - What proportion of women refers moderate to severe pain during office hysteroscopy with a mini- hysteroscope? A systematic review and meta- analysis Margarida Cordoeiro, Susana Lima Oliveira, Maria Helena Solheiro, António Santos-Paulo, Vera Afreixo P25 - Fetal hemoglobin level impact on the clinical and laboratory profile of SCA patients Ariana Freire, Vera Afreixo, Vanusa Rocha, Enrique Martinez, José Raya, João Gonçalves P26 - Effectiveness of neural mobilization techniques in decreasing pain and improving function in people with low back and neck pain: a systematic review with meta-analysis Frederico Baptista, Ellen Nery, Eduardo B. Cruz, Vera Afreixo, Anabela G. Silva P27 - Bacterial co-infections in patients with COVID-19: a retrospective single center study Raquel Diaz, Vera Afreixo, Filipa Rocha, Gabriela Nogueira, Bruno Gago. P28 - Forecast model for Performance Indicators, a case of USF Arte Nova Catarina Cardoso, José P. Antunes P29 - Hypertensive disorders in pregnancy: association between clinic and ambulatory blood pressure and adverse pregnancy outcomes Eline S. Barbosa, José M. Bastos P30 - Patients pain and anxiety in office hysteroscopy Maria Francisca Vilaça, Catarina Toscano, António Santos Paulo, Vera Afreixo P31 - Modelling COVID-19 with graph theory and cellular automata as an alternative to overcome the limitations of the SIR model. Rodrigo Antunes, Sofia J. Pinheiro, Cristiana J. Silva, Vera Afreixo, Pedro Rebelo, Rui Pedro Leitão P32 - Determinants of surgical site infection in hip and knee arthroplasty: A retrospective cohort study Catarina Alves Rodrigues, Cristina Nunes, Sandra Linhares, Cristiano Matos P33 - The dimension reduction power of ClustOfVar: application of the variable cluster analysis technique in a mixed data health database Natacha Oliveira, Milton Severo P34 - Coping strategies and psychosocial factors at work of dietitians/ nutritionists: a multivariate analysis approach Raquel Simões, João Oliveira, Pedro Sá-Couto, Marco Ramos P35 - Are coping and workplace psychosocial factors related to work ability in physicians? A PLS-SEM approach Joana Ricardo Pires, Pedro Sá Couto, Pedro Bem-Haja, Marco Ramos P36 - Occupational health, well-being and ability to work in a sample of Portuguese Nurses Diana Lucas, Hugo Senra, Vitor Rodrigues, Pedro Sá Couto, Marco Ramos P37 - Exploratory and inferential analysis of children's eye defects screening in the region of Aveiro Diana Lucas, Joana C. Santos, Jorge M. S. Marques, Rui P. Leitão P38 - Physicians’ perceptions of psychosocial factors and coping strategies in their ability to work: a multivariate analysis Pedro Couto, Ana Messias, Marta Estrela, Pedro Sá Couto, Marco Ramos P39 - Neutrophil-to-lymphocyte ratio as a prognostic marker in highly PD-L1 expressing advanced non-small cell lung cancer patients in first line treatment with Pembrolizumab Joana Dias, Lídia Gomes, Ana Figueiredo, Fernando Barata
The impact of vaccination on transmission and death by COVID-19: an observational study in Portugal’s biggest primary care cluster
Vaccines are a key tool to manage the COVID-19 pandemic by preventing infection, hospitalization, severe disease, or death. In Portugal, information on vaccine effectiveness in real-life settings is still limited. Therefore, the main goal of this study is to evaluate the association between vaccination against COVID-19 and mortality and transmissibility in the population of the biggest Primary Care Cluster in Portugal, ACES Baixo Vouga (ACES BV). A retrospective, observational study including all reported cases of COVID-19 in ACES BV between December 2020 and September 2021 was conducted (N=18,415). Anonymized data on demographic, clinical, epidemiological characteristics and outcomes of interest of the COVID-19 confirmed cases were collected. To model vaccination’s association with death, a logistic regression analysis was performed. To estimate the effect of vaccination on the number of secondary cases, a zero-inflated negative binomial model was used. Of 18,415 confirmed cases included in this study, 1,981 (10.8%) were vaccinated. A complete vaccination scheme against COVID-19 (OR=0.22, CI95 0.09-0.47) and female sex (OR=0.42, CI95 0.30-0.57) protected against death, while age (OR=1.12, CI95 1.10-1.13), comorbidities (OR=4.14, CI95 2.27- 8.34) and the presence of symptoms (OR=1.72, CI95 2.27-8.34) increased the odds of death. A complete vaccination scheme (RR 0.63, CI95 0.49–0.81) decreased the risk for the number of secondary cases in the model without outliers. It is vital to monitor the vaccination effects in the real world and to better understand the characteristics of COVID-19 vaccine-induced immunity.
Direitos de Autor (c) 2022 Sofia Tedim, Tiago Pinho-Bandeira, Rui Pedro Leitão, Cristiana Silva, Sofia J Pinheiro, Vera Afreixo, Ana Oliveira
Meta-analysis of Chemical exposure and increased risk of hematologic malignancies.
Background: Exposure to environmental risk factors may be associated with the development of hematologic malignancies, as pointed by evidence in the literature. Despite this, most studies refer to a specific risk factor or disease. Objective: To assess this issue globally, in this study we performed a meta-analysis. Methods: A searched PubMed database was done in 2020 and a selection of 35 case-control and cohort studies published between 1990 and 2020 was done. Results: Was observed a significant adverse association between exposure to organic solvents such as benzene and incidence of myeloid malignancies. For agricultural chemicals (pesticides, herbicides, insecticides), an adverse association was found for both lymphoid and myeloid malignancies. Conclusions: The results suggest that activities in chemical industries or agriculture pose greater risk and should be closely monitored. Prospective occupational surveys are needed to identify exposure–response relationships and clarify disease mechanisms.
Direitos de Autor (c) 2022 Gisela Ferreira, Vera Afreixo, Adela Iutis, Raquel Silva
Effects of temperature and mobility on COVID-19 incidence
Background/Objective: The purpose of this study was to evaluate the association between COVID-19 weekly case numbers with the trend, average temperature (AT) and mobility (MOB) at the national level and by regions, in Portugal. Methods: We compiled a weekly dataset including COVID-19 case numbers, average temperature and mobility during the period of March 23, 2020, to August 30, 2022. Negative binomial regression was fitted to estimate the effect of covariates on the COVID-19 case numbers. Results: We observed a significant increasing effect over time in most regions, negative temperature effect, in all regions, and a positive mobility effect, in most regions, on the number of cases using a two-week lag. Conclusion: Increased mobility and low temperatures were associated with higher numbers of cases of COVID-19 infection.
Direitos de Autor (c) 2022 Vanusa Rocha, Vera Afreixo, Nelson Sousa
Fonseca anamnestic index for screening Temporomandibular Disorders - reliability to discriminate muscular from intra-articular disorders.
Background/ Objective: Fonseca anamnestic index (FAI) is a simple and quick survey used for screening the presence and severity of Temporomandibular Disorders (TMD). The presented study aimed to screen the FAI accuracy to discriminate different types of TMD: intra-articular (AD), Masticatory Muscular Disorder (MMD), or the presence of both typologies. Methods: The existence of a pattern in the FAI based on the frequency of answers was evaluated and supported by other variables: sex, age, medical diagnosis and Visual Analog Scale of health-related quality of Life (VASLife). The non-parametric Chi-square test () or Fisher's exact test were used to assess the existence of associations between these variables. In the pairs of variables where such association was identified, its intensity was measured by Cramér's V Coefficient. The prediction if FAI could be a good decision tool for distinguish the type of TMD was assessed through logistic regression models (ordinal and multinomial). Results: The higher FAI score was associated with questions related with temporomandibular joint (TMJ) pain, TMJ clicks and person anxiety. Severe cases classified by FAI are correlated with typology of Both (AD+MMD). Moreover, the female patients presented more moderate and severe cases in FAI and also correlated with the presence of AD+MMD. The logistic model showed low accuracy to distinguish the TMD typology (~70%). Conclusion: FAI is a good initial methodology in TMD diagnosis, however integrated in a logistic regression model for distinguish the typology of TMD has proved to be insufficient. It is expected that the combination of this survey with other outcomes will make the model more accurate.
Intra-articular temporomandibular Disorders
Masticatory muscle temporomandibular disorders
Direitos de Autor (c) 2022 Ricardo Miguel Vieira de São João, PhD, Henrique José Cardoso, PhD, David Sanz, MD, David Faustino Ângelo, MD, PhD
Transition to parenthood recognition and accepting the maternal role.
Direitos de Autor (c) 2022 Sandra Maria Campinos Rodrigues
Mortality prediction scores in burn patients – a comparative analysis
Introduction: The aim of this study consisted of accuracy assessment and comparison of different mortality prediction models performance used in the burn population from our burns unit (BU), comparing survivors and non-survivors clinical and demographic characteristics. Methods: A retrospective study of adult burn patients admitted to our BU in a 5-year period was performed. Toxic epidermal necrolysis and polytraumatized patients were not included. Mortality rate was assessed. Survivors and non-survivors clinical and sociodemographic characteristics were analyzed and compared. Four models were included, namely Abbreviated Burn Severity Index (ABSI), Belgian Outcome in Burn Injury (BOBI), revised-Baux and Ryan model. Observed and predicted mortality were compared using Hosmer-Lemeshow test for models goodness-of-fit, receiver operating curves (ROC) and area under curve (AUC) for discriminative performance evaluation. Results: Our cohort consisted of 641 patients, in which 58,2% were male. Patients mean age was 60.02 ± 18.97 years and total burned surface area (TBSA) was 12.94 ± 15.11 %. Third degree burns were present in 71% and inhalation injury in 12.3%. Observed mortality rate was 9.4% (n=60). Non-survivors were significantly older (73 vs. 60 years; p<0.001), had a larger TBSA (27.75 vs. 7%; p<0.001), higher frequency of third-degree burns (96.7 vs. 68.3%; p<0.001) and inhalation injury (31,7% vs. 10,3%; p<0.001), but no gender significant difference was verified. All models demonstrated an adequate goodness-of-fit, all with p-values >0.05 in Hosmer-Lemeshow test assessment. Revised-Baux (AUC 0.870 ± 0.025), ABSI (AUC 0.850 ± 0.026) and BOBI (AUC 0.831 ± 0.026) have demonstrated good discriminative power and Ryan model (0.774 ± 0.030) was only moderate. Discussion: The four models revealed proper predictive performance, with revised-Baux presenting as the most accurate model for mortality prediction. Their use in the BU represents a practical and valuable tool for risk stratification, treatment appropriateness and improve the burns care quality control.
Direitos de Autor (c) 2022 Gonçalo Tomé Ferreira
Exploratory Analysis based on Relative Risk on the incidence of different causes of death in mortality in the Region of Aveiro
Direitos de Autor (c) 2022 Diana Lucas Almeida, Renato Rodrigues
Análise do padrão de Trauma Oral e Maxillofacial no mundo: Uma Revisão Sistemática e Meta-Análise
Objetivo do trabalho: O objetivo desta revisão foi determinar a prevalências das lesões oro-maxilo-faciais e a sua relação com o sexo, a idade e a etiologia das mesmas no mundo. Materiais e Métodos: Todos os artigos publicados em inglês em base de dados Google Académico, EBSCO, PubMed, NCBI, Medline, ELSEVIER e SCOPUS foram revistos no âmbito de lesões oro-maxilo-faciais no mundo durante os últimos 11 anos, entre 2010-2020. Utilizamos a Lista de Verificação do Instituto Joanna Briggs para a avaliar o Risco de Viés e o sistema de GRADE (Grading of Recommendations Assessment, Development and Evaluation) foi aplicado para avaliação da qualidade da evidência. Os estudos foram distribuídos em cinco grupos de países: Ásia, África, América Latina, Europa e Regiões muçulmanas. Resultados e Conclusões: Os resultados mostram que os acidentes de viação (55,37%) foram o tipo de trauma mais frequente, seguido de agressões (17,56%) e quedas (10,21%). As fraturas foram as lesões mais prevalentes (84,3%). Foi possível estabelecer uma associação entre os acidentes de viação e os países asiáticos. As agressões são mais frequentes em África, predominantemente masculinas, enquanto as quedas aumentam com a idade, entre as mulheres, nos países europeus. As fraturas são geralmente observadas nas regiões muçulmanas.
Direitos de Autor (c) 2022 Cristiana Palmela Pereira, Catarina Gonçalves, Fátima Brilhante, Adriana Santos, Ana Rodrigues, Diana Augusto, Francisco Salvado, Rui Santos
Epidemiologia do Padrão e Etiologia do Traumatismo Oral e MaxiloFacial: Estudo retrospetivo em Hospital Central Português
Objetivo Avaliar a etiologia e os tipos de lesões oro-maxilofaciais mais frequentes em Portugal. Materiais e métodos Um estudo observacional clínico epidemiológico foi realizado no Centro Hospitalar Lisboa Norte com uma amostra de 384 indivíduos diagnosticados com trauma oro-maxilofacial, entre os anos de 2018 e 2020. Os dados foram recolhidos doa registos clínicos e analisados no SPSS, versão 27. Resultados Ambos os sexos apresentaram uma distribuição homogénea, 49,5 sexo feminino e 50,5%g sexo masculino. Em 2020 verifica-se uma diminuição no número de traumas em comparação com os demais anos. As quedas foram a etiologia mais frequente (44,3%), seguida da agressão (24,7%). Os incisivos centrais superiores (174) foram os dentes mais afetados com fraturas não complicadas da coroa e o tratamento mais frequente foi a prescrição de analgésicos. Conclusão Existe uma relação entre quedas, mulheres e aumento da idade, e entre agressão e homens adultos. As quedas e agressões são as principais etiologias e o ano de 2020 apresenta um declínio no número de traumas devido à atual situação de pandemia.
Direitos de Autor (c) 2022 Cristiana Palmela Pereira, Catarina Gonçalves, Diana Augusto, Francisco Coutinho, Francisco Salvado, Rui Santos
Purpose in life and caregiver burden in kidney failure: Preliminary results from a hierarchical multiple regression analysis
Direitos de Autor (c) 2022 Helena Sousa, Oscar Ribeiro, Daniela Silva, Alan Christensen, Daniela Figueiredo
Portugal teve o primeiro caso de COVID-19 a 2 de março de 2020. No mês seguinte foram registados 81.087 novos casos e 266 mortes tendo a Direção Geral de Saúde adotado medidas de controlo da pandemia, entre as quais o isolamento social. Esta medida contribuiu para a perturbação na rotina dos cuidadores familiares (CF), verificando-se um aumento de tensão, distress e sobrecarga, provocados pela necessidade de conciliar novos procedimentos às rotinas de cuidado existentes, afetando a saúde mental dos CF e despoletando sentimentos de solidão, ansiedade, depressão e insónia. Neste contexto, o isolamento social emergente da pandemia, associado a outros fatores já existentes, podem ter contribuído para fragilizar ainda mais a saúde física e mental dos cuidadores. O objetivo deste estudo é identificar os efeitos do isolamento social decorrente da pandemia por COVID-19 na saúde mental dos CF de pessoas dependentes/pessoal mais velhas.
Direitos de Autor (c) 2022 Inês Magalhães, B.A., Lisneti Castro, PhD, Blezi Santos, PhD, Marília Rua, PhD
Caregiver burden and family functioning – the moderating effect of educational level
Direitos de Autor (c) 2022 José Joaquim Alvarelhão, Sónia Silva, Helena Loureiro