Effects of Di-(2-ethylhexyl) phthalate on vascular smooth muscle cells

Abstract

Every year million tons of plastic are produced around the world and humans are increasingly exposed to them. This constant exposure has raised some concerns against human health and substances leaching from plastics, such as phthalates. These compounds, used to give flexibility to polyvinyl chloride (PVC), are endocrine-disrupting compounds because they have the ability to interfere with hormone pathways. Phthalates are not covalently bound to the plastic, which makes them susceptible to go to the atmosphere, foods and consequently into body fluids. [...]